AutoCAD 2010 :: No Panels Or Ribbons Loaded

I never do any in depth changes to my cui.  It won't load ribbons or panels because it claims that my cui file is removed, renamed, or missing.  It is not, I can specify it in the AutoCAD options (the second picture link).  But when I type in cui, It gives me the error message (the first picture link).  I've restarted and it does nothing.  I've verified that the acad.cuix file is there... and it is (aka not removed, renamed, or missing so the error is bogus)  The only strange thing I found though was that when I do a cui load, I can browse to the file, select it, but when I click to load, nothing happens.  No hourglass cursor, no hiccup, not anything.  If I repeat the same process with a different cui file, it works as it should. URLs...