Photoshop :: Saving In CS6 Extended

For some reason, some times when I am saving a file I will get an error message stating that the "file cannot be saved as it is in use by another program". The problem lies in that there is not another program open, let alone running the file that I am currently using. Many times Bridge is the only other program even running.This doesn't happen all the time, but more often than not and it is incredibly frustrating because I end up having to attempt to save at least 3 times before it decides to actually do the deed and nothing will have actually changed. No programs closed or anything, just at least 3 seperate attempts to save before it does.this has been going on since I purchased and after a couple months and a few updates I just don't know what else to do.