Photoshop :: Generator And CSS Sprites

if one decides to follow the Generator workflow, how would it be best to still take advantage of css sprites ? The new Generator workflow certainly has great potential for an improved workflow offering obvious time savings. I know the entire picture has not yet been filled with Reflow still being developed, but currently, what would be a great way to achieve the advantages of this workflow while still using css sprites ?
 
I guess a separate layer or file, would have to be created entirely for the sprites and used in Dreamweaver separately ? one can still include the sprite layer in the .psd file but simply not give that layer a file extension ? as far as i know Reflow does not support positioning images with css, the way one will in Dreamweaver for css sprites.
 
Google specifically recommends css sprites. Even if one adjusts the quality with the Generator output, you still end up with a bunch of images, each of which would be a request to the server. Seems that this method as compared to slicing, would potentially end up with even more images and hence a slower loading page.