Photoshop :: Can CS5 Remove Padding From Tileset / Tilesheet

I'm a game designer, and I work with a lot of tiles extracted from existing tilesets I find on the web. I used to crop and save each desired tile one at a time until I discovered that I could split the sheet into slices and save them all at once, saving tons of time.

I ran into a problem, though. Some tilesets are padded, meaning that there is space between each tile on the tileset image. Is there a way for photoshop to either remove the padding and "collapse" the tiles together into an unpadded tileset, or can I somehow configure the slices to accommodate for the padding?